Nanotechnology In Cancer
Nanotechnologies are also being investigated to deliver immunotherapy. Standalone nanoparticle vaccines are also being designed to raise sufficient T cell response to eradicate tumors, through co-delivery of antigen and adjuvant, the inclusion of multiple antigens to stimulate multiple dendritic cell targets, and continuous release of antigens for prolonged immune stimulation. Molecular blockers of immune-suppressive factors produced can also be co-encapsulated in nanoparticle vaccines to alter the immune context of tumors and improve response, an approach being pursued in the Nano Approaches to Modulate Host Cell Response for Cancer Therapy Center at UNC.
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