Gastric Cancer stem cells
Gastricepithelium is continuously regenerated by gastric stem cells, which give rise to various kinds of daughter cells, including parietal cells, chief cells, surface mucous cells, mucous neck cells, and enter endocrine cells. Recently, it was hypothesized that cancer stem cells drive the cancer growth and metastasis. In contrast to conventional clonal evolution hypothesis, only cancer stem cells can initiate tumor formation, self-renew, and differentiate into various kinds of daughter cells. we review here how critical signaling pathways, including hedgehog, Want, Notch, epidermal growth factor, and bone morphogenetic protein signaling, may regulate the self-renewal and differentiation of gastric stem cells and gastric cancer stem cells.
Related Conference of Gastric Cancer stem cells
April 21-22, 2025
16th International Conference on Cancer Stem Cell & Oncology Research
Amsterdam, Netherlands
November 24-25, 2025
47th Euro-Global Summit on Cancer Therapy & Radiation Oncology
Barcelona, Spain
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